This Doe ID episode is a bit different from most other ones, because the victim in this case is alive and well. In August, 1971, when Melissa Highsmith was just 22 months old, her mother Alta; desperate for a babysitter, allowed a stranger she didn't know to watch over her little girl in Fort Worth, Texas. Alta was terrified when the woman never contacted her again, and took Melissa with her. The woman had provided Alta with fake information, and no real way to contact her. With not much to go on, police were not much help. Alta prayed and believed in her heart that the woman who took Melissa did so because she wanted a little girl and would raise her and keep her safe.

New Years’ Day 1985 should have rung in an exciting new year for Patti Stichler and her three young daughters.  Instead, in the middle of the night on January 1-2, someone slashed and stabbed Patti to death in her bedroom.  Her three girls, ages 11, 9 and 6, were in their bedrooms just feet away.  The oldest, Andrea, was the one to find her mom, and also found the most significant clue the police had – the open window in the blood-stained bathroom, and the gaping curtains that had been cut away from it. A knife sheath was found right outside, but the killer eluded police for decades.  Sylvania, OH investigators focused on people Patti knew, but could not link anyone in her inner circle to the crime. Decades later, a very complex forensic genealogy analysis that required interpreting one-sided DNA matches, piercing adoption records, and a lot of luck, finally provided a name – and it was not who anyone suspected.

In December, 1990, a couple discovered a human skull on an abandoned farm on Oscar Talley Road near Lanagan, Missouri. A search of the area by police revealed more bones, and clothing. The remains were determined to be that of a woman, but she carried no ID. A white towel had been wrapped around the woman's head, and she was tied with several types of bindings made up of ropes, cords, and coax cables. Due to the state of decomposition, the cause and manner of death could not be determined, but police were confident that the woman had been the victim of a homicide. The dead woman was given the name 'Oscar Talley Road Jane Doe' and police went about trying to figure out how she died and who was responsible; but first, they needed to find out their victim's name, and it would take decades. Along the way, her remains would even be misplaced, and finding them became an investigation within the investigation. In 2021, after more than three decades, genealogy and DNA were used to identify 'Oscar Talley Road Jane Doe' as Shawna Beth Garber. She was 22 years old when she died in 1990.