13 year-old Blanca Elisa Roberson, who went by Elisa, vanished on Sunday August 6,1989 in Arkansas Pass, TX as she walked a short distance from her home to the Kieberger Elementary School to meet a friend. Her friend waited for her at the school, but Elisa never showed up. Later investigation would lead to multiple witnesses who saw Elisa on her walk that day, and despite one of them saying that they saw her get into a Maroon car, police have never been later to find her. Later, despite eyewitnesses seeing Elisa walking just before she vanished, police seemed to turn their suspicion to Elisa's own family. Eventually a search of the home they lived in when Elisa went missing was searched for clues, but despite law enforcement threatening that an arrest was imminent, one never came. Elisa's family is angered by police suspicion of them, and they have a favorite suspect of their own, one who police said had an alibi, but the family remains suspicious of him. Decades later, it seems like this case is at a standstill. In this episode, Elisa's sister Ruby discusses this mysterious and heartbreaking disappearance.

24 year old Jennifer Kesse vanished in Orlando, Florida on January 24th ,2006. People that knew Jennifer best, right away were concerned, because Jennifer was an organized professional who would never go off on a whim. Her car, a black 2004 Chevrolet Malibu was missing from it's parking spot in front of her condo in the up and coming Mosaic at Millenia condo complex. On January 26th, after seeing the news of Jennifer's disappearance on the news, someone called in a tip that her car could be found at the Huntington on the Green Condominiums, about a mile from her home. Police went to the scene and verified that her car was indeed parked at the seedy Huntington on the Green Condominiums, about a mile from her home, but there was no sign of Jennifer. Police caught a break when they reviewed grainy surveillance photos of the car being parked there, and they were shocked to see that Jennifer was not the person who exited the vehicle. Instead, they could see that a slim person, possibly a male standing between 5ft3 and 5ft5 had parked the card and left on foot. Unfortunately, a fence in the surveillance photos obstructed the view of the driver's face. Dogs tracked the scent from Jennifer's car right back to her condo development leading to suspicions that the person who likely abducted her had walked back to Jennifer's condo complex, and perhaps had reason to be there. It came to light that Jennifer had been wary of some men who were working at her condo complex in the days before she vanished. Police tried to investigate some of those men, but ran into hurdles when they found that the company that employed them did not keep proper records, sometimes paid under the table, and often hired people that were in the country illegally. One tip led to a man named Chino who had worked at the apartment complex. While he may have had information about what happened to Jennifer, he reportedly cooperated with investigators.

Jennifer's case eventually went cold but became a popular one in the media and on online discussion forums. Jennifer's family, feeling that things were at a standstill and feeling underwhelmed by the investigation, sued the Orlando PD in order to obtain case files and have the case re-investigated by another agency

Rusty Meye was a man who was down on his luck. Living alone in a rented Vero Beach, Florida mobile home, he had battled depression, drinking and overuse of medication brought on by a terrible foot injury he suffered that left him disabled. Rusty had made the decision to stop drinking and not rely on his medications anymore, and was making progress in his life. However, one thing he still faced was financial issues, and an ongoing butting of heads with his landlord who wanted Rusty to find a new place to live. Rusty recounted to people close to him that his landlord constantly verbally abused him, and even threatened to burn the trailer to the ground with Rusty inside it. According to Rusty, the landlord would come into the trailer when he wasn't home. Things were clearly not good for Rusty. Then, on October 17, 2020, 59 year old Rusty Meye was reported missing by his landlord of all people. All of belongings were left behind in his trailer, including his phone, keys, and a wallet with cash inside. Outside of the trailer, Rusty's cars were there. The only thing missing was Rusty himself.